Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria

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Medicinal plant extracts with efflux inhibitory activity against Gram-negative bacteria.

It was hypothesised that extracts from plants that are used as herbal medicinal products contain inhibitors of efflux in Gram-negative bacteria. Extracts from 21 plants were screened by bioassay for synergy with ciprofloxacin against Salmonella enterica serotype Typhimurium, including mutants in which acrB and tolC had been inactivated. The most active extracts, fractions and purified compounds...

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In Vitro Antibacterial Activity of Several Plant Extracts and Oils against Some Gram-Negative Bacteria

Background: Medicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in the treatment of antibiotic-resistant bacteria. The aim of this study was to evaluate the antibacterial activity of 28 plant extracts and oils against four Gram-negative bacterial species.Methods: Experimental, in vitro, evaluation of the activities of 28 plant extract...

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In Vitro Antibacterial Activity of Several Plant Extracts and Oils against Some Gram-Negative Bacteria

BACKGROUND Medicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in the treatment of antibiotic-resistant bacteria. The aim of this study was to evaluate the antibacterial activity of 28 plant extracts and oils against four Gram-negative bacterial species. METHODS Experimental, in vitro, evaluation of the activities of 28 plant extrac...

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in vitro antibacterial activity of several plant extracts and oils against some gram-negative bacteria

background: medicinal plants are considered new resources for producing agents that could act as alternatives to antibiotics in the treatment of antibiotic-resistant bacteria. the aim of this study was to evaluate the antibacterial activity of 28 plant extracts and oils against four gram-negative bacterial species. methods: experimental, in vitro, evaluation of the activities of 28 plant extrac...

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The Impact of Efflux Pump Inhibitors on the Activity of Selected Non-Antibiotic Medicinal Products against Gram-Negative Bacteria.

The potential role of non-antibiotic medicinal products in the treatment of multidrug-resistant Gram-negative bacteria has recently been investigated. It is highly likely that the presence of efflux pumps may be one of the reasons for the weak activity of non-antibiotics, as in the case of some non-steroidal anti-inflammatory drugs (NSAIDs), against Gram-negative rods. The activity of eight dru...

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ژورنال

عنوان ژورنال: International Journal of Antimicrobial Agents

سال: 2011

ISSN: 0924-8579

DOI: 10.1016/j.ijantimicag.2010.10.027